Veteran actor and comedian Dave Coulier has revealed a new cancer diagnosis, delivering difficult news just months after he was declared cancer-free. The 66-year-old “Full House” star disclosed on December 2, 2025, that he is now being treated for early-stage p16 squamous carcinoma, a form of tongue cancer. This development arrives after his earlier 2024 battle with stage-3 non-Hodgkin lymphoma — a fight many believed he had won.
Early Detection, New Diagnosis
Coulier’s new diagnosis emerged during what he thought was a routine check-up. In October 2025, a PET scan revealed an abnormality at the base of his tongue. Although an initial biopsy came back negative, a second scan later that month showed growth — prompting further testing, including a CT scan, MRI, and a deeper biopsy. Doctors ultimately confirmed p16 squamous carcinoma, unrelated to his previous lymphoma.
He has begun a course of 35 radiation treatments, scheduled to conclude December 31, 2025. Despite the sudden turn, Coulier says his prognosis is strong: early-stage p16 squamous carcinoma can be highly treatable, with physicians placing his odds of recovery at over 90%.
A Tough Year — and a New Mission
Just nine months ago, Coulier celebrated being declared cancer-free after enduring aggressive chemotherapy for non-Hodgkin lymphoma. The remission came in spring 2025 following months of grueling treatment. That relief was short-lived.
On the latest “Today” show broadcast, he described the new cancer as “a shock to the system.” He acknowledged the emotional toll on his wife, Melissa Bring, and the strain such a diagnosis places on loved ones. Still — even in the wake of this second battle — Coulier is leaning into advocacy.
He said that the first cancer indirectly saved his life by leading to regular check-ups, which ultimately caught the second cancer early. He urged others to stay vigilant with screenings such as colonoscopies, mammograms, and prostate exams. His message: early detection can save lives — sometimes more than once.
Turning Pain Into Purpose
Inspired by his health journey, Coulier has also launched a new enterprise: a digital marketplace called AwareMarket, dedicated to toxin-free, holistic products. The concept was born during his chemotherapy treatments, when he became acutely aware of the countless chemicals and potentially harmful substances in everyday household items. Through AwareMarket, he hopes to help others live healthier lives — and plans to direct a portion of proceeds toward cancer research.
In addition to his advocacy, Coulier has found joy in newly becoming a grandfather as of March 2025; he has said that this life milestone fuels his determination to recover and raise awareness.
What This Means — and Why It Matters
Coulier’s second cancer diagnosis so soon after remission serves as a powerful reminder: cancer can recur, even after apparent victory. But his story also underscores something equally important — the life-saving potential of routine check-ups, follow-up scans, and vigilance.
By speaking openly, Coulier transforms a deeply personal struggle into a broader public message about health, prevention, and hope.
If you or someone you care about has postponed regular screenings, consider scheduling them — early detection can make all the difference.
We’re wishing Dave Coulier strength and healing — and encourage readers to share their thoughts or experiences in the comments below.
