Cleto Escobedo III, the longtime bandleader of Jimmy Kimmel Live!, passed away on November 11, 2025, at the age of 59. His death has left fans, friends, and fellow musicians heartbroken, all asking one question — how did Cleto Escobedo pass away?
While the exact cause of his passing has not been officially confirmed by his family or representatives, several close associates have shared that Escobedo had been battling ongoing health issues in recent months. Reports indicate that his death may have been related to complications following a liver procedure, though no official statement has been made public.
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A Beloved Musician and Friend
Cleto Escobedo wasn’t just a talented saxophonist — he was a symbol of loyalty, laughter, and lifelong friendship. Born in Las Vegas, Nevada, in 1966, he grew up surrounded by music, inspired by his father, Cleto Escobedo Jr., who was also a saxophonist. Music ran through his veins from a young age, and his natural talent quickly became evident.
His journey to national fame began long before television. Escobedo toured with several big names, including Paula Abdul and Earth, Wind & Fire, showcasing his incredible versatility across genres. Yet, his most famous role would come years later, when his childhood friend Jimmy Kimmel invited him to lead the house band on Jimmy Kimmel Live!
Cleto and Jimmy: A Lifelong Friendship
The bond between Cleto Escobedo and Jimmy Kimmel was more than professional — it was brotherly. The two met as kids in Las Vegas, and their friendship blossomed over decades. When Kimmel launched his late-night show in 2003, there was no question about who would lead the band.
Together, they built Jimmy Kimmel Live! into one of America’s most beloved late-night programs. Escobedo’s warm smile, quick humor, and musical brilliance became part of the show’s identity. His chemistry with Kimmel created a comfort and authenticity that audiences loved.
Behind the scenes, Kimmel often described Cleto as his “right-hand man” and “lifelong brother.” Their relationship transcended work — it was rooted in loyalty and shared history.
Recent Health Battles
In the months leading up to his death, Escobedo had taken a step back from public appearances. Fans noticed his absence from Jimmy Kimmel Live! episodes and began to express concern online.
Though details remain private, people close to him shared that Escobedo had undergone a medical procedure related to his liver. He had been optimistic about his recovery, but complications reportedly arose that impacted his health. Despite battling these issues, he remained upbeat and connected with close friends and family.
His passing on November 11 shocked many, as the show’s team and fans had been hopeful for his return to the stage.
How Did Cleto Escobedo Pass Away?
To address the question directly — how did Cleto Escobedo pass away — the cause of death has not yet been publicly confirmed. However, information from those near him suggests he experienced medical complications linked to an existing liver condition.
Escobedo’s family has requested privacy as they mourn, and no formal medical statement has been issued. What’s certain, however, is that his passing was sudden and unexpected.
The loss is not only felt by his loved ones but by millions of fans who have watched him perform night after night for more than two decades.
An Irreplaceable Part of Late-Night Television
For over 20 years, Cleto Escobedo III brought life to late-night television through his infectious energy and incredible musical skill. Whether he was laughing with Kimmel during opening monologues or leading the band through high-energy performances, his presence elevated the show’s spirit.
His ability to mix jazz, funk, and pop gave Jimmy Kimmel Live! a sound all its own — vibrant, soulful, and unmistakably fun. Every time Escobedo took the stage, he made the audience feel like part of something special.
Even casual viewers could feel the camaraderie between him and Kimmel. Their jokes, their playful banter, and their mutual admiration made viewers feel as though they were watching two lifelong friends doing what they loved most — creating joy.
Tributes from Fans and Friends
After news of his passing broke, social media filled with emotional tributes from fans and celebrities alike.
- Musicians remembered him as one of the kindest souls in the industry.
- Fans recalled moments from the show that made them laugh or smile.
- Jimmy Kimmel himself shared a deeply emotional message, calling Cleto “a brother for life.”
The late-night host expressed gratitude for their decades of friendship, describing Escobedo as “someone who made every day brighter.” It was a rare and moving statement that showed just how much Cleto meant to those closest to him.
A Musical Legacy That Lives On
Cleto Escobedo’s musical influence extended beyond television. His talent inspired countless young musicians, particularly those from Hispanic and Latino communities, to pursue careers in performance and production.
He was admired not only for his skills but for his humility. Despite his fame, he treated everyone with respect — from fellow artists to fans who approached him for photos after tapings.
Escobedo’s sound became part of the cultural fabric of modern television. His saxophone solos, vibrant smile, and unwavering positivity made him unforgettable.
His passing is a reminder that behind the music and lights are real people who pour their hearts into their art — and Cleto Escobedo did that every single night.
The Human Side of His Story
Cleto Escobedo’s life story wasn’t one of overnight fame but of steady dedication. He worked tirelessly behind the scenes, always putting others before himself. He rarely sought the spotlight, even as he performed for millions each week.
Those who knew him personally describe him as kind, generous, and always willing to help others. He was proud of his heritage, his family, and his craft. He loved to laugh, loved good food, and loved to share stories about growing up in Las Vegas with Jimmy Kimmel and their circle of childhood friends.
For Kimmel and the Jimmy Kimmel Live! crew, losing Cleto isn’t just the loss of a musician — it’s losing part of their family.
Remembering His Final Legacy
While the world awaits official confirmation of how Cleto Escobedo passed away, what stands out most is not the details of his death, but the impact of his life.
He proved that music and friendship could transcend fame. His loyalty to Kimmel, his devotion to his family, and his passion for performing made him one of the most respected figures in entertainment.
Even in his final months, Escobedo continued to inspire others. His courage in facing health challenges with grace and optimism set an example for everyone who followed his journey.
The Road Ahead for Jimmy Kimmel Live!
The Jimmy Kimmel Live! family now faces the challenge of continuing without one of its founding members. While the show will go on, Cleto’s absence will be deeply felt.
Fans can expect a tribute segment in the coming weeks celebrating his life and career. Viewers have already begun sharing their favorite Cleto moments — from his funny reactions to guests to his legendary saxophone solos.
It’s clear that Cleto Escobedo III’s presence shaped the identity of Jimmy Kimmel Live! in ways that will last forever.
Final Thoughts
So, how did Cleto Escobedo pass away? While the full medical details remain private, his passing came after a period of serious health issues. What we do know is that the world lost a remarkable artist, a loyal friend, and a kindhearted soul.
His music, laughter, and legacy will live on — not just in reruns or recordings, but in the hearts of those who watched him light up the stage for over two decades.
Cleto Escobedo may be gone, but his rhythm, friendship, and spirit will continue to echo through every note he ever played. Share your memories or thoughts below to honor his incredible life and lasting influence.
